Investigating Substitutions in Antibody–Antigen Complexes Using Molecular Dynamics: A Case Study with Broad-spectrum, Influenza A Antibodies

In studying the binding of host antibodies to the surface antigens of pathogens, the structural and functional characterization of antibody–antigen complexes by X-ray crystallography and binding assay is important. However, the characterization requires experiments that are typically time consuming...

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Detalles Bibliográficos
Autores principales: Lees, William D., Stejskal, Lenka, Moss, David S., Shepherd, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309259/
https://www.ncbi.nlm.nih.gov/pubmed/28261207
http://dx.doi.org/10.3389/fimmu.2017.00143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309259/
https://www.ncbi.nlm.nih.gov/pubmed/28261207
http://dx.doi.org/10.3389/fimmu.2017.00143

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