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N-Acetylglutaminoyl-S-farnesyl-l-cysteine (SIG-1191): an anti-inflammatory molecule that increases the expression of the aquaglyceroporin, aquaporin-3, in human keratinocytes

Isoprenylcysteine (IPC) small molecules were discovered as signal transduction modulating compounds ~25 years ago. More recently, IPC molecules have demonstrated antioxidant and anti-inflammatory properties in a variety of dermal cells as well as antimicrobial activity, representing a novel class of...

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Detalles Bibliográficos
Autores principales: Fernández, José R., Webb, Corey, Rouzard, Karl, Voronkov, Michael, Huber, Kristen L., Stock, Jeffry B., Stock, Maxwell, Gordon, Joel S., Perez, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309294/
https://www.ncbi.nlm.nih.gov/pubmed/27988893
http://dx.doi.org/10.1007/s00403-016-1708-x