Store‐operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells

KEY POINTS: Depletion of Ca(2+) stores activates store‐operated channels (SOCs), which mediate Ca(2+) entry pathways that regulate cellular processes such as contraction, proliferation and gene expression. In vascular smooth muscle cells (VSMCs), stimulation of SOCs composed of canonical transient r...

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Detalles Bibliográficos
Autores principales: Shi, Jian, Miralles, Francesc, Birnbaumer, Lutz, Large, William A., Albert, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Molecular and cellular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309361/
https://www.ncbi.nlm.nih.gov/pubmed/27753095
http://dx.doi.org/10.1113/JP273302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309361/
https://www.ncbi.nlm.nih.gov/pubmed/27753095
http://dx.doi.org/10.1113/JP273302

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