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TNF Blockade Maintains an IL-10(+) Phenotype in Human Effector CD4(+) and CD8(+) T Cells

CD4(+) and CD8(+) effector T cell subpopulations can display regulatory potential characterized by expression of the prototypically anti-inflammatory cytokine IL-10. However, the underlying cellular mechanisms that regulate expression of IL-10 in different T cell subpopulations are not yet fully elu...

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Detalles Bibliográficos
Autores principales: Roberts, Ceri A., Durham, Lucy E., Fleskens, Veerle, Evans, Hayley G., Taams, Leonie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309392/
https://www.ncbi.nlm.nih.gov/pubmed/28261215
http://dx.doi.org/10.3389/fimmu.2017.00157