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Impaired Surface Expression of HLA-DR, TLR2, TLR4, and TLR9 in Ex Vivo-In Vitro Stimulated Monocytes from Severely Injured Trauma Patients

Objective. Trauma patients (TP) frequently develop an imbalanced immune response that often causes infectious postinjury complications. Monocytes show a diminished capability of both producing proinflammatory cytokines and antigen presentation after trauma. TLR2, TLR4, and TLR9 recognize pathogens a...

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Detalles Bibliográficos
Autores principales: Heftrig, David, Sturm, Ramona, Oppermann, Elsie, Kontradowitz, Kerstin, Jurida, Katrin, Schimunek, Lukas, Woschek, Mathias, Marzi, Ingo, Relja, Borna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309437/
https://www.ncbi.nlm.nih.gov/pubmed/28255201
http://dx.doi.org/10.1155/2017/2608349