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Bile acids potentiate proton‐activated currents in Xenopus laevis oocytes expressing human acid‐sensing ion channel (ASIC1a)

Acid‐sensing ion channels (ASICs) are nonvoltage‐gated sodium channels transiently activated by extracellular protons and belong to the epithelial sodium channel (ENaC)/Degenerin (DEG) family of ion channels. Bile acids have been shown to activate two members of this family, the bile acid‐sensitive...

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Detalles Bibliográficos
Autores principales: Ilyaskin, Alexandr V., Diakov, Alexei, Korbmacher, Christoph, Haerteis, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309578/
https://www.ncbi.nlm.nih.gov/pubmed/28193786
http://dx.doi.org/10.14814/phy2.13132