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A unique Pd-catalysed Heck arylation as a remote trigger for cyclopropane selective ring-opening

Combining functionalization at a distant position from a reactive site with the creation of several consecutive stereogenic centres, including the formation of a quaternary carbon stereocentre, in acyclic system represents a pinnacle in organic synthesis. Here we report the regioselective Heck aryla...

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Detalles Bibliográficos
Autores principales: Singh, Sukhdev, Bruffaerts, Jeffrey, Vasseur, Alexandre, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309700/
https://www.ncbi.nlm.nih.gov/pubmed/28169276
http://dx.doi.org/10.1038/ncomms14200