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Nanoparticle-linked antagonist for leptin signaling inhibition in breast cancer

AIM: To develop a leptin peptide receptor antagonist linked to nanoparticles and determine its effect on viability of breast cancer cells. METHODS: The leptin antagonist, LPrA2, was coupled via EDAC [1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide] to iron oxide nanoparticles (IONP-LPrA2) to increase...

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Detalles Bibliográficos
Autores principales:	Harmon, Tia, Harbuzariu, Adriana, Lanier, Viola, Lipsey, Crystal C, Kirlin, Ward, Yang, Lily, Gonzalez-Perez, Ruben R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309714/ https://www.ncbi.nlm.nih.gov/pubmed/28246585 http://dx.doi.org/10.5306/wjco.v8.i1.54

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