The Biophysical Probes 2-fluorohistidine and 4-fluorohistidine: Spectroscopic Signatures and Molecular Properties

Fluorinated amino acids serve as valuable biological probes, by reporting on local protein structure and dynamics through (19)F NMR chemical shifts. 2-fluorohistidine and 4-fluorohistidine, studied here with DFT methods, have even more capabilities for biophysical studies, as their altered pK(a) val...

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Detalles Bibliográficos
Autores principales: Kasireddy, Chandana, Ellis, Jonathan M., Bann, James G., Mitchell-Koch, Katie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309746/
https://www.ncbi.nlm.nih.gov/pubmed/28198426
http://dx.doi.org/10.1038/srep42651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309746/
https://www.ncbi.nlm.nih.gov/pubmed/28198426
http://dx.doi.org/10.1038/srep42651

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