Cargando…
The Biophysical Probes 2-fluorohistidine and 4-fluorohistidine: Spectroscopic Signatures and Molecular Properties
Fluorinated amino acids serve as valuable biological probes, by reporting on local protein structure and dynamics through (19)F NMR chemical shifts. 2-fluorohistidine and 4-fluorohistidine, studied here with DFT methods, have even more capabilities for biophysical studies, as their altered pK(a) val...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309746/ https://www.ncbi.nlm.nih.gov/pubmed/28198426 http://dx.doi.org/10.1038/srep42651 |