RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome

Necroptosis is a type of programmed cell death with great significance in many pathological processes. Tumour necrosis factor-α(TNF), a proinflammatory cytokine, is a prototypic trigger of necroptosis. It is known that mitochondrial reactive oxygen species (ROS) promote necroptosis, and that kinase...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Su, Sheng Sean, Zhao, Shubo, Yang, Zhentao, Zhong, Chuan-Qi, Chen, Xin, Cai, Qixu, Yang, Zhang-Hua, Huang, Deli, Wu, Rui, Han, Jiahuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309790/
https://www.ncbi.nlm.nih.gov/pubmed/28176780
http://dx.doi.org/10.1038/ncomms14329

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309790/
https://www.ncbi.nlm.nih.gov/pubmed/28176780
http://dx.doi.org/10.1038/ncomms14329

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