Cargando…

Microenvironment-derived factors driving metastatic plasticity in melanoma

Cellular plasticity is a state in which cancer cells exist along a reversible phenotypic spectrum, and underlies key traits such as drug resistance and metastasis. Melanoma plasticity is linked to phenotype switching, where the microenvironment induces switches between invasive/MITF(LO) versus proli...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Isabella S., Heilmann, Silja, Kansler, Emily R., Zhang, Yan, Zimmer, Milena, Ratnakumar, Kajan, Bowman, Robert L., Simon-Vermot, Theresa, Fennell, Myles, Garippa, Ralph, Lu, Liang, Lee, William, Hollmann, Travis, Xavier, Joao B., White, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309794/
https://www.ncbi.nlm.nih.gov/pubmed/28181494
http://dx.doi.org/10.1038/ncomms14343