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Microenvironment-derived factors driving metastatic plasticity in melanoma
Cellular plasticity is a state in which cancer cells exist along a reversible phenotypic spectrum, and underlies key traits such as drug resistance and metastasis. Melanoma plasticity is linked to phenotype switching, where the microenvironment induces switches between invasive/MITF(LO) versus proli...
Autores principales: | Kim, Isabella S., Heilmann, Silja, Kansler, Emily R., Zhang, Yan, Zimmer, Milena, Ratnakumar, Kajan, Bowman, Robert L., Simon-Vermot, Theresa, Fennell, Myles, Garippa, Ralph, Lu, Liang, Lee, William, Hollmann, Travis, Xavier, Joao B., White, Richard M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309794/ https://www.ncbi.nlm.nih.gov/pubmed/28181494 http://dx.doi.org/10.1038/ncomms14343 |
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