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Epstein–Barr virus particles induce centrosome amplification and chromosomal instability

Infections with Epstein–Barr virus (EBV) are associated with cancer development, and EBV lytic replication (the process that generates virus progeny) is a strong risk factor for some cancer types. Here we report that EBV infection of B-lymphocytes (in vitro and in a mouse model) leads to an increase...

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Detalles Bibliográficos
Autores principales: Shumilov, Anatoliy, Tsai, Ming-Han, Schlosser, Yvonne T., Kratz, Anne-Sophie, Bernhardt, Katharina, Fink, Susanne, Mizani, Tuba, Lin, Xiaochen, Jauch, Anna, Mautner, Josef, Kopp-Schneider, Annette, Feederle, Regina, Hoffmann, Ingrid, Delecluse, Henri-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309802/
https://www.ncbi.nlm.nih.gov/pubmed/28186092
http://dx.doi.org/10.1038/ncomms14257