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Conformational changes in intact dengue virus reveal serotype-specific expansion

Dengue virus serotype 2 (DENV2) alone undergoes structural expansion at 37 °C (associated with host entry), despite high sequence and structural homology among the four known serotypes. The basis for this differential expansion across strains and serotypes is unknown and necessitates mapping of the...

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Detalles Bibliográficos
Autores principales: Lim, Xin-Xiang, Chandramohan, Arun, Lim, Xin Ying Elisa, Bag, Nirmalya, Sharma, Kamal Kant, Wirawan, Melissa, Wohland, Thorsten, Lok, Shee-Mei, Anand, Ganesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309819/
https://www.ncbi.nlm.nih.gov/pubmed/28186093
http://dx.doi.org/10.1038/ncomms14339