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Conformational changes in intact dengue virus reveal serotype-specific expansion
Dengue virus serotype 2 (DENV2) alone undergoes structural expansion at 37 °C (associated with host entry), despite high sequence and structural homology among the four known serotypes. The basis for this differential expansion across strains and serotypes is unknown and necessitates mapping of the...
Autores principales: | Lim, Xin-Xiang, Chandramohan, Arun, Lim, Xin Ying Elisa, Bag, Nirmalya, Sharma, Kamal Kant, Wirawan, Melissa, Wohland, Thorsten, Lok, Shee-Mei, Anand, Ganesh S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309819/ https://www.ncbi.nlm.nih.gov/pubmed/28186093 http://dx.doi.org/10.1038/ncomms14339 |
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