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PDI regulates seizure activity via NMDA receptor redox in rats

Redox modulation of cysteine residues is one of the post-translational modifications of N-methyl-D-aspartate receptor (NMDAR). Protein disulfide isomerases (PDI), an endoplasmic reticulum (ER) chaperone, plays a crucial role in catalyzing disulfide bond formation, reduction, and isomerization. In th...

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Detalles Bibliográficos
Autores principales: Kim, Ji Yang, Ko, Ah-Rhem, Hyun, Hye-Won, Min, Su-Ji, Kim, Ji-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309844/
https://www.ncbi.nlm.nih.gov/pubmed/28198441
http://dx.doi.org/10.1038/srep42491