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GARP2 accelerates retinal degeneration in rod cGMP-gated cation channel β-subunit knockout mice

The Cngb1 locus-encoded β-subunit of rod cGMP-gated cation channel and associated glutamic acid rich proteins (GARPs) are required for phototransduction, disk morphogenesis, and rod structural integrity. To probe individual protein structure/function of the GARPs, we have characterized several trans...

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Detalles Bibliográficos
Autores principales: DeRamus, Marci L., Stacks, Delores A., Zhang, Youwen, Huisingh, Carrie E., McGwin, Gerald, Pittler, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309851/
https://www.ncbi.nlm.nih.gov/pubmed/28198469
http://dx.doi.org/10.1038/srep42545