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GARP2 accelerates retinal degeneration in rod cGMP-gated cation channel β-subunit knockout mice
The Cngb1 locus-encoded β-subunit of rod cGMP-gated cation channel and associated glutamic acid rich proteins (GARPs) are required for phototransduction, disk morphogenesis, and rod structural integrity. To probe individual protein structure/function of the GARPs, we have characterized several trans...
Autores principales: | DeRamus, Marci L., Stacks, Delores A., Zhang, Youwen, Huisingh, Carrie E., McGwin, Gerald, Pittler, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309851/ https://www.ncbi.nlm.nih.gov/pubmed/28198469 http://dx.doi.org/10.1038/srep42545 |
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