The TNF-α antagonist etanercept reverses age-related decreases in colonic SERT expression and faecal output in mice

Treatment for chronic constipation in older people is challenging and the condition has a major impact on quality of life. A lack of understanding about the causes of this condition has hampered the development of effective treatments. 5-HT is an important pro-kinetic agent in the colon. We examined...

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Detalles Bibliográficos
Autores principales: Patel, Bhavik Anil, Fidalgo, Sara, Wang, Chunfang, Parmar, Leena, Mandona, Kasonde, Panossian, Annabelle, Flint, Melanie S., Ranson, Richard N., Saffrey, M. Jill, Yeoman, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309893/
https://www.ncbi.nlm.nih.gov/pubmed/28198447
http://dx.doi.org/10.1038/srep42754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309893/
https://www.ncbi.nlm.nih.gov/pubmed/28198447
http://dx.doi.org/10.1038/srep42754

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