Optogenetic control of cellular forces and mechanotransduction

Contractile forces are the end effectors of cell migration, division, morphogenesis, wound healing and cancer invasion. Here we report optogenetic tools to upregulate and downregulate such forces with high spatiotemporal accuracy. The technology relies on controlling the subcellular activation of Rh...

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Detalles Bibliográficos
Autores principales: Valon, Léo, Marín-Llauradó, Ariadna, Wyatt, Thomas, Charras, Guillaume, Trepat, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309899/
https://www.ncbi.nlm.nih.gov/pubmed/28186127
http://dx.doi.org/10.1038/ncomms14396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309899/
https://www.ncbi.nlm.nih.gov/pubmed/28186127
http://dx.doi.org/10.1038/ncomms14396

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