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IRAV (FLJ11286), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10

Dengue virus (DENV) is a member of the genus Flavivirus and can cause severe febrile illness. Here, we show that FLJ11286, which we refer to as IRAV, is induced by DENV in an interferon-dependent manner, displays antiviral activity against DENV, and localizes to the DENV replication complex. IRAV is...

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Detalles Bibliográficos
Autores principales: Balinsky, Corey A., Schmeisser, Hana, Wells, Alexandra I., Ganesan, Sundar, Jin, Tengchuan, Singh, Kavita, Zoon, Kathryn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309953/
https://www.ncbi.nlm.nih.gov/pubmed/27974568
http://dx.doi.org/10.1128/JVI.01606-16