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Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals

BACKGROUND: Human aging is associated with profound changes in one of the major epigenetic mechanisms, DNA methylation. Some of these changes occur in a clock-like fashion, i.e., correlating with the calendar age of an individual, thus providing a new aging biomarker. Some reports have identified fa...

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Detalles Bibliográficos
Autores principales: Nevalainen, Tapio, Kananen, Laura, Marttila, Saara, Jylhävä, Juulia, Mononen, Nina, Kähönen, Mika, Raitakari, Olli T., Hervonen, Antti, Jylhä, Marja, Lehtimäki, Terho, Hurme, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310016/
https://www.ncbi.nlm.nih.gov/pubmed/28289477
http://dx.doi.org/10.1186/s13148-016-0301-7