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Partial HIV C2V3 envelope sequence analysis reveals association of coreceptor tropism, envelope glycosylation and viral genotypic variability among Kenyan patients on HAART

BACKGROUND: HIV-1 is highly variable genetically and at protein level, a property it uses to subvert antiviral immunity and treatment. The aim of this study was to assess if HIV subtype differences were associated with variations in glycosylation patterns and co-receptor tropism among HAART patients...

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Detalles Bibliográficos
Autores principales: Kitawi, Rose C., Hunja, Carol W., Aman, Rashid, Ogutu, Bernhards R., Muigai, Anne W. T., Kokwaro, Gilbert O., Ochieng, Washingtone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310022/
https://www.ncbi.nlm.nih.gov/pubmed/28196510
http://dx.doi.org/10.1186/s12985-017-0703-y