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Metabolite toxicity determines the pace of molecular evolution within microbial populations

BACKGROUND: The production of toxic metabolites has shaped the spatial and temporal arrangement of metabolic processes within microbial cells. While diverse solutions to mitigate metabolite toxicity have evolved, less is known about how evolution itself is affected by metabolite toxicity. We hypothe...

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Detalles Bibliográficos
Autores principales: Lilja, Elin E., Johnson, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310025/
https://www.ncbi.nlm.nih.gov/pubmed/28196465
http://dx.doi.org/10.1186/s12862-017-0906-2