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Metabolite toxicity determines the pace of molecular evolution within microbial populations
BACKGROUND: The production of toxic metabolites has shaped the spatial and temporal arrangement of metabolic processes within microbial cells. While diverse solutions to mitigate metabolite toxicity have evolved, less is known about how evolution itself is affected by metabolite toxicity. We hypothe...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310025/ https://www.ncbi.nlm.nih.gov/pubmed/28196465 http://dx.doi.org/10.1186/s12862-017-0906-2 |