PI3Kα isoform-dependent activation of RhoA regulates Wnt5a-induced osteosarcoma cell migration

BACKGROUND: We have reported that the phosphatidylinositol-3 kinase (PI3K)/Akt signaling pathway mediated Wnt5a-induced osteosarcoma cell migration. However, the signaling pathways regulating Wnt5a/PI3K/Akt-mediated cell migration remains poorly defined in osteosarcoma cells. METHODS: We evaluated t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Ailiang, Yan, Ting, Wang, Kun, Huang, Zhihui, Liu, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310072/
https://www.ncbi.nlm.nih.gov/pubmed/28289332
http://dx.doi.org/10.1186/s12935-017-0396-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310072/
https://www.ncbi.nlm.nih.gov/pubmed/28289332
http://dx.doi.org/10.1186/s12935-017-0396-8

Ejemplares similares