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Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

BACKGROUND: Reactive microglia have been associated with the histological changes that occur in Parkinson’s disease brains and mouse models of the disease. Multiple studies from autopsy brains have verified the presence of microgliosis in several brain regions including substantia nigra, striatum, h...

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Detalles Bibliográficos
Autores principales: Manocha, Gunjan Dhawan, Floden, Angela Marie, Puig, Kendra Lynn, Nagamoto-Combs, Kumi, Scherzer, Clemens R., Combs, Colin Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310074/
https://www.ncbi.nlm.nih.gov/pubmed/28196514
http://dx.doi.org/10.1186/s13024-017-0158-z