Cargando…

Defining the contribution of neuroinflammation to Parkinson’s disease in humanized immune system mice

BACKGROUND: Reactive microglia have been associated with the histological changes that occur in Parkinson’s disease brains and mouse models of the disease. Multiple studies from autopsy brains have verified the presence of microgliosis in several brain regions including substantia nigra, striatum, h...

Descripción completa

Detalles Bibliográficos
Autores principales:	Manocha, Gunjan Dhawan, Floden, Angela Marie, Puig, Kendra Lynn, Nagamoto-Combs, Kumi, Scherzer, Clemens R., Combs, Colin Kelly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310074/ https://www.ncbi.nlm.nih.gov/pubmed/28196514 http://dx.doi.org/10.1186/s13024-017-0158-z

Ejemplares similares

IGF-1R Inhibitor Ameliorates Neuroinflammation in an Alzheimer’s Disease Transgenic Mouse Model
por: Sohrabi, Mona, et al.
Publicado: (2020)

Anti-α4β1 Integrin Antibodies Attenuated Brain Inflammatory Changes in a Mouse Model of Alzheimer’s Disease
por: Manocha, Gunjan, et al.
Publicado: (2018)

Attenuation of microglial activation in a mouse model of Alzheimer’s disease via NFAT inhibition
por: Rojanathammanee, Lalida, et al.
Publicado: (2015)

Amyloid Precursor Protein Mediated Changes in Intestinal Epithelial Phenotype In Vitro
por: Puig, Kendra L., et al.
Publicado: (2015)

Potential Role of Intracranial Mast Cells in Neuroinflammation and Neuropathology Associated with Food Allergy
por: Germundson, Danielle L., et al.
Publicado: (2022)

Amyloid Precursor Protein and Proinflammatory Changes Are Regulated in Brain and Adipose Tissue in a Murine Model of High Fat Diet-Induced Obesity
por: Puig, Kendra L., et al.
Publicado: (2012)

Sex-Dependent Effects of Intestinal Microbiome Manipulation in a Mouse Model of Alzheimer’s Disease
por: Kaur, Harpreet, et al.
Publicado: (2021)

Characterization of Novel Src Family Kinase Inhibitors to Attenuate Microgliosis
por: Manocha, Gunjan D., et al.
Publicado: (2015)

HLA-II-Dependent Neuroimmune Changes in Group A Streptococcal Necrotizing Fasciitis
por: Ambigapathy, Ganesh, et al.
Publicado: (2023)

Asymptomatic sensitization to a cow’s milk protein induces sustained neuroinflammation and behavioral changes with chronic allergen exposure
por: Brishti, Afrina, et al.
Publicado: (2022)

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease
por: Dhawan, Gunjan, et al.
Publicado: (2012)

Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy
por: Smith, Nicholas A., et al.
Publicado: (2019)

Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells
por: Germundson, Danielle L., et al.
Publicado: (2018)

Palmitic Acid-Enriched Diet Increases α-Synuclein and Tyrosine Hydroxylase Expression Levels in the Mouse Brain
por: Schommer, Jared, et al.
Publicado: (2018)

Beta amyloid oligomers and fibrils stimulate differential activation of primary microglia
por: Sondag, Cindy M, et al.
Publicado: (2009)

HLA-II Alleles Influence Physical and Behavioral Responses to a Whey Allergen in a Transgenic Mouse Model of Cow's Milk Allergy
por: Germundson, Danielle L., et al.
Publicado: (2022)

The Contribution of Microglia to Neuroinflammation in Parkinson’s Disease
por: Badanjak, Katja, et al.
Publicado: (2021)

Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain
por: Puig, Kendra L., et al.
Publicado: (2017)

A Pilot Study to Assess Effects of Long-Term Inhalation of Airborne Particulate Matter on Early Alzheimer-Like Changes in the Mouse Brain
por: Bhatt, Dhaval P., et al.
Publicado: (2015)

Glycosphingolipids and neuroinflammation in Parkinson’s disease
por: Belarbi, Karim, et al.
Publicado: (2020)

Update on the treatment of Parkinson’s disease psychosis: role of pimavanserin
por: Combs, Brianna L, et al.
Publicado: (2017)

A simplified and sensitive immunoprecipitation approach for the analysis of HSF1 in murine liver tissue
por: Trivedi, Rachana, et al.
Publicado: (2021)

Sex Steroids Effects on Asthma: A Network Perspective of Immune and Airway Cells
por: Borkar, Niyati A., et al.
Publicado: (2022)

Biomarker of Neuroinflammation in Parkinson’s Disease
por: Liu, Tsai-Wei, et al.
Publicado: (2022)

Regulatory role of TRIM21 in the type-I interferon pathway in Japanese encephalitis virus-infected human microglial cells
por: Manocha, Gunjan Dhawan, et al.
Publicado: (2014)

Striatal Neuroinflammation Promotes Parkinsonism in Rats
por: Choi, Dong-Young, et al.
Publicado: (2009)

Cyclooxygenase and Neuroinflammation in Parkinson’s Disease Neurodegeneration
por: Bartels, Anna L, et al.
Publicado: (2010)

Linking Neuroinflammation and Neurodegeneration in Parkinson's Disease
por: Gelders, Géraldine, et al.
Publicado: (2018)

Epigenetic Regulation of Neuroinflammation in Parkinson’s Disease
por: Rasheed, Madiha, et al.
Publicado: (2021)

Microglia Mediated Neuroinflammation in Parkinson’s Disease
por: Isik, Sevim, et al.
Publicado: (2023)

Iba1 immunoreactivity is enhanced following an antigen retrieval treatment with EDTA, pH 6.0
por: Ghatak, Atreyi, et al.
Publicado: (2014)

A protocol for making and sectioning multiple embedded Swiss-rolls in a gelatin matrix
por: Sohrabi, Mona, et al.
Publicado: (2019)

Adhesion of monocytes to type I collagen stimulates an APP-dependent proinflammatory signaling response and release of Aβ1-40
por: Sondag, Cindy M, et al.
Publicado: (2010)

Liver Bile Acid Changes in Mouse Models of Alzheimer’s Disease
por: Kaur, Harpreet, et al.
Publicado: (2021)

The Involvement of Neuroinflammation and Kynurenine Pathway in Parkinson's Disease
por: Zinger, Anna, et al.
Publicado: (2011)

The Endotoxin-Induced Neuroinflammation Model of Parkinson's Disease
por: Tufekci, Kemal Ugur, et al.
Publicado: (2011)

Translation Imaging in Parkinson’s Disease: Focus on Neuroinflammation
por: Belloli, Sara, et al.
Publicado: (2020)

Locus Coeruleus Modulates Neuroinflammation in Parkinsonism and Dementia
por: Giorgi, Filippo Sean, et al.
Publicado: (2020)

Neuroinflammation and protein pathology in Parkinson’s disease dementia
por: Kouli, Antonina, et al.
Publicado: (2020)

Neuroinflammation in Parkinson’s Disease and its Treatment Opportunities
por: Çınar, Elif, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gp0g6c1d06pas4a8jeda67ben9