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Enhancing circadian clock function in cancer cells inhibits tumor growth

BACKGROUND: Circadian clocks control cell cycle factors, and circadian disruption promotes cancer. To address whether enhancing circadian rhythmicity in tumor cells affects cell cycle progression and reduces proliferation, we compared growth and cell cycle events of B16 melanoma cells and tumors wit...

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Detalles Bibliográficos
Autores principales: Kiessling, Silke, Beaulieu-Laroche, Lou, Blum, Ian D., Landgraf, Dominic, Welsh, David K., Storch, Kai-Florian, Labrecque, Nathalie, Cermakian, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310078/
https://www.ncbi.nlm.nih.gov/pubmed/28196531
http://dx.doi.org/10.1186/s12915-017-0349-7