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Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics

A simple, precise, selective and fast ultra-high performance liquid chromatography (UHPLC-UV) method has been developed and validated for the simultaneous determination of a lipid regulating agent fenofibrate and its metabolite fenofibric acid in rat plasma. The chromatographic separation was carrie...

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Detalles Bibliográficos
Autores principales: Alamri, Rayan G., Mohsin, Kazi, Ahmad, Ajaz, Raish, Mohammad, Alanazi, Fars K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310137/
https://www.ncbi.nlm.nih.gov/pubmed/28223873
http://dx.doi.org/10.1016/j.jsps.2016.05.008