Cargando…

Development and validation of bioanalytical UHPLC-UV method for simultaneous analysis of unchanged fenofibrate and its metabolite fenofibric acid in rat plasma: Application to pharmacokinetics

A simple, precise, selective and fast ultra-high performance liquid chromatography (UHPLC-UV) method has been developed and validated for the simultaneous determination of a lipid regulating agent fenofibrate and its metabolite fenofibric acid in rat plasma. The chromatographic separation was carrie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alamri, Rayan G., Mohsin, Kazi, Ahmad, Ajaz, Raish, Mohammad, Alanazi, Fars K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310137/ https://www.ncbi.nlm.nih.gov/pubmed/28223873 http://dx.doi.org/10.1016/j.jsps.2016.05.008

Ejemplares similares

Development of self-nanoemulsifying drug delivery systems for the enhancement of solubility and oral bioavailability of fenofibrate, a poorly water-soluble drug
por: Mohsin, Kazi, et al.
Publicado: (2016)

Role of Alternative Lipid Excipients in the Design of Self-Nanoemulsifying Formulations for Fenofibrate: Characterization, in vitro Dispersion, Digestion and ex vivo Gut Permeation Studies
por: Alshamsan, Aws, et al.
Publicado: (2018)

A Review of Currently Available Fenofibrate and Fenofibric Acid Formulations
por: Ling, Hua, et al.
Publicado: (2013)

Preparation and pharmacokinetic study of fenofibrate cubic liquid crystalline
por: Wei, Shijie, et al.
Publicado: (2017)

A review on the rationale and clinical use of concomitant rosuvastatin and fenofibrate/fenofibric acid therapy
por: Strain, Joe D, et al.
Publicado: (2010)

Fibrane the reduced derivative of fenofibrate
por: Kotheimer, Amanda E., et al.
Publicado: (2019)

Comparison of efficacy and safety of choline fenofibrate (fenofibric acid) to micronized fenofibrate in patients of mixed dyslipidemia: A randomized, open-label, multicenter clinical trial in Indian population
por: Patel, Piyush, et al.
Publicado: (2016)

Rosiglitazone and Fenofibrate Additive Effects on Lipids
por: Slim, Ahmad, et al.
Publicado: (2011)

Detecting responses to treatment with fenofibrate in pedigrees
por: Cherlin, Svetlana, et al.
Publicado: (2018)

Effect of Fenofibrate Medication on Renal Function
por: Kim, Sungjong, et al.
Publicado: (2017)

Fenofibrate-induced renal dysfunction, yes or no?
por: Emami, Fatemeh, et al.
Publicado: (2020)

The role of fenofibrate in the treatment of COVID-19
por: Yasmin, Farah, et al.
Publicado: (2021)

Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481]
Publicado: (2005)

Evaluation of the Pharmacokinetic Drug–Drug Interaction between Micronized Fenofibrate and Pitavastatin in Healthy Volunteers
por: Lee, Hae Won, et al.
Publicado: (2020)

Fenofibrate: direct attenuating effects on tumor growth
por: Kapoor, Shailendra
Publicado: (2013)

Uridine Prevents Fenofibrate-Induced Fatty Liver
por: Le, Thuc T., et al.
Publicado: (2014)

Pleiotropic effects of fenofibrate therapy on rats with hypertriglycemia
por: Sun, Bing, et al.
Publicado: (2015)

Anticancer Properties of Fenofibrate: A Repurposing Use
por: Lian, Xin, et al.
Publicado: (2018)

Identifying fenofibrate responsive CpG sites
por: Cantor, Rita, et al.
Publicado: (2018)

Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential()()
por: Stalinska, J., et al.
Publicado: (2019)

Anti-inflammatory role of fenofibrate in treating diseases
por: Jin, Lv, et al.
Publicado: (2023)

Fenofibrate Inhibited the Differentiation of T Helper 17 Cells In Vitro
por: Zhou, Zhou, et al.
Publicado: (2012)

Fenofibrate in Primary Biliary Cirrhosis: A Pilot Study
por: Liberopoulos, E.N, et al.
Publicado: (2010)

Effects of fenofibrate on inflammatory cytokines in diabetic retinopathy patients
por: Ju, Hai-Bing, et al.
Publicado: (2017)

Effect of fenofibrate on uric acid level in patients with gout
por: Jung, Ju-Yang, et al.
Publicado: (2018)

Fenofibrate and Impaired Taste Perception in Type 2 Diabetes
por: Davis, Timothy M.E.
Publicado: (2020)

Fenofibrate: Hepatotoxicity, pulmonary toxicity and eosinophilia: case report
Publicado: (2022)

Indirect Neonatal Hyperbilirubinemia and the Role of Fenofibrate as an Adjuvant to Phototherapy
por: Shabo, Salam K., et al.
Publicado: (2023)

A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption
por: Back, Hyun-moon, et al.
Publicado: (2018)

Development and Validation of RP-HPLC Method for Simultaneous Estimation of Atorvastatin Calcium and Fenofibrate in Tablet Dosage Forms
por: Jain, N., et al.
Publicado: (2008)

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment
por: Kazi, Mohsin, et al.
Publicado: (2019)

Effect of fenofibrate on microcirculation and wound healing in healthy and diabetic mice
por: Valentin, S, et al.
Publicado: (2009)

Should We Start All Patients with Diabetic Retinopathy on Fenofibrates?
por: Koshy, Jacob, et al.
Publicado: (2013)

Effect of Fenofibrate in Combination with Urate Lowering Agents in Patients with Gout
por: Lee, You-Hyun, et al.
Publicado: (2006)

Fenofibrate Therapy in Carnitine Palmitoyl Transferase Type 2 Deficiency
por: Hamilton-Craig, I., et al.
Publicado: (2012)

Fenofibrate Induces Ketone Body Production in Melanoma and Glioblastoma Cells
por: Grabacka, Maja M., et al.
Publicado: (2016)

Fenofibrate Nanocrystals Embedded in Oral Strip-Films for Bioavailability Enhancement
por: Kevadiya, Bhavesh D., et al.
Publicado: (2018)

Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
por: Mohammed, Fayeza, et al.
Publicado: (2017)

Fenofibrate improves vascular endothelial function and contractility in diabetic mice
por: Xu, Nan, et al.
Publicado: (2018)

Fenofibrate: A Nonlithogenic Means of Recurrent Drug-Induced Pancreatitis
por: Kassim, Thamer, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pog0k82b88vg8ee2vqf0p4077j