Cargando…

Prediction of the effect of formulation on the toxicity of chemicals

Two approaches for the prediction of which of two vehicles will result in lower toxicity for anticancer agents are presented. Machine-learning models are developed using decision tree, random forest and partial least squares methodologies and statistical evidence is presented to demonstrate that the...

Descripción completa

Detalles Bibliográficos
Autores principales: Mistry, Pritesh, Neagu, Daniel, Sanchez-Ruiz, Antonio, Trundle, Paul R., Vessey, Jonathan D., Gosling, John Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310521/
https://www.ncbi.nlm.nih.gov/pubmed/28261444
http://dx.doi.org/10.1039/c6tx00303f