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Stochastic models of gene transcription with upstream drives: exact solution and sample path characterization
Gene transcription is a highly stochastic and dynamic process. As a result, the mRNA copy number of a given gene is heterogeneous both between cells and across time. We present a framework to model gene transcription in populations of cells with time-varying (stochastic or deterministic) transcripti...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310734/ https://www.ncbi.nlm.nih.gov/pubmed/28053113 http://dx.doi.org/10.1098/rsif.2016.0833 |