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Basic studies on epigenetic carcinogenesis of low-dose exposure to 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) in vitro

1-Trichloromethyl-1,2,3,4-tetrahydro-β-carboline (TaClo) has been widely studied as a neurotoxic substance, however, only few reports have explored its effect on carcinogenicity. Since the aberrant modification of DNA methylation occurs very early in almost all human cancers, the focus of this study...

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Detalles Bibliográficos
Autores principales: Wang, Renjie, Cui, Yi, Xu, Yi, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310788/
https://www.ncbi.nlm.nih.gov/pubmed/28199384
http://dx.doi.org/10.1371/journal.pone.0172243