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One reporter for in-cell activity profiling of majority of protein kinase oncogenes

In-cell profiling enables the evaluation of receptor tyrosine activity in a complex environment of regulatory networks that affect signal initiation, propagation and feedback. We used FGF-receptor signaling to identify EGR1 as a locus that strongly responds to the activation of a majority of the rec...

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Detalles Bibliográficos
Autores principales: Gudernova, Iva, Foldynova-Trantirkova, Silvie, Ghannamova, Barbora El, Fafilek, Bohumil, Varecha, Miroslav, Balek, Lukas, Hruba, Eva, Jonatova, Lucie, Jelinkova, Iva, Bosakova, Michaela Kunova, Trantirek, Lukas, Mayer, Jiri, Krejci, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310841/
https://www.ncbi.nlm.nih.gov/pubmed/28199182
http://dx.doi.org/10.7554/eLife.21536