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GSK3 is a metabolic checkpoint regulator in B cells

B cells predominate in a quiescent state until antigen is encountered, which results in rapid growth, proliferation and differentiation. These distinct cell states are likely accompanied by differing metabolic needs, yet little is known about the metabolic control of B cell fate. Here we show that g...

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Detalles Bibliográficos
Autores principales: Jellusova, Julia, Cato, Matthew H., Apgar, John R., Ramezani-Rad, Parham, Leung, Charlotte, Chen, Cindi, Richardson, Adam D., Conner, Elaine M., Benschop, Robert J., Woodgett, James R., Rickert, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310963/
https://www.ncbi.nlm.nih.gov/pubmed/28114292
http://dx.doi.org/10.1038/ni.3664