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Recurrent RNA motifs as scaffolds for genetically encodable small molecule biosensors

Allosteric RNA devices are increasingly viewed as important tools capable of monitoring enzyme evolution, optimizing engineered metabolic pathways, facilitating gene discovery and regulators of nucleic acid-based therapeutics. A key bottleneck in the development of these platforms is the availabilit...

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Detalles Bibliográficos
Autores principales: Porter, Ely B., Polaski, Jacob T., Morck, Makenna M., Batey, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310984/
https://www.ncbi.nlm.nih.gov/pubmed/28092358
http://dx.doi.org/10.1038/nchembio.2278