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Direct control of regulatory T cells by keratinocytes

Environmental challenges to epithelial cells trigger gene expression changes that elicit context-appropriate immune responses. Here we show that the chromatin remodeler Mi-2β controls epidermal homeostasis by regulating genes involved in keratinocyte and immune-cell activation to maintain an inactiv...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Mariko, Hosoi, Junichi, Lai, Jen-Feng, Brissette, Janice, Ziegler, Steven F., Morgan, Bruce A., Georgopoulos, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310986/
https://www.ncbi.nlm.nih.gov/pubmed/28092372
http://dx.doi.org/10.1038/ni.3661