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Direct control of regulatory T cells by keratinocytes
Environmental challenges to epithelial cells trigger gene expression changes that elicit context-appropriate immune responses. Here we show that the chromatin remodeler Mi-2β controls epidermal homeostasis by regulating genes involved in keratinocyte and immune-cell activation to maintain an inactiv...
Autores principales: | Kashiwagi, Mariko, Hosoi, Junichi, Lai, Jen-Feng, Brissette, Janice, Ziegler, Steven F., Morgan, Bruce A., Georgopoulos, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310986/ https://www.ncbi.nlm.nih.gov/pubmed/28092372 http://dx.doi.org/10.1038/ni.3661 |
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