Selective molecular impairment of spontaneous neurotransmission modulates synaptic efficacy

Recent studies suggest that stimulus-evoked and spontaneous neurotransmitter release processes are mechanistically distinct. Here we targeted the non-canonical synaptic vesicle SNAREs Vps10p-tail-interactor-1a (vti1a) and vesicle-associated membrane protein 7 (VAMP7) to specifically inhibit spontane...

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Detalles Bibliográficos
Autores principales: Crawford, Devon C., Ramirez, Denise M. O., Trauterman, Brent, Monteggia, Lisa M., Kavalali, Ege T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311059/
https://www.ncbi.nlm.nih.gov/pubmed/28186166
http://dx.doi.org/10.1038/ncomms14436

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311059/
https://www.ncbi.nlm.nih.gov/pubmed/28186166
http://dx.doi.org/10.1038/ncomms14436

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