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GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

Stem cell factor (SCF), the ligand of c-kit, is a key cytokine for hematopoiesis. Hematopoietic precursors express c-kit, whereas differentiated cells of hematopoietic lineage are negative for this receptor, with the exception of NK cells, mast cells, and a few others. While it has long been recogni...

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Detalles Bibliográficos
Autores principales: Barroeta Seijas, Amairelys Belen, Simonetti, Sonia, Vitale, Sara, Runci, Daniele, Quinci, Angela Caterina, Soriani, Alessandra, Criscuoli, Mattia, Filippi, Irene, Naldini, Antonella, Sacchetti, Federico Maria, Tarantino, Umberto, Oliva, Francesco, Piccirilli, Eleonora, Santoni, Angela, Di Rosa, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311071/
https://www.ncbi.nlm.nih.gov/pubmed/28261209
http://dx.doi.org/10.3389/fimmu.2017.00147