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MicroRNA-155 promotes the pathogenesis of experimental colitis by repressing SHIP-1 expression

AIM: To explore the mechanism by which microRNA-155 (miR-155) regulates the pathogenesis of experimental colitis. METHODS: A luciferase assay was performed to confirm the binding of miR-155 to the SHIP-1 3’-UTR. MiR-155 mimics, negative controls and SHIP-1 expression/knockdown vectors were establish...

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Detalles Bibliográficos
Autores principales: Lu, Zhan-Jun, Wu, Jian-Jiong, Jiang, Wei-Liang, Xiao, Jun-Hua, Tao, Kai-Zhong, Ma, Lei, Zheng, Ping, Wan, Rong, Wang, Xing-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311107/
https://www.ncbi.nlm.nih.gov/pubmed/28246471
http://dx.doi.org/10.3748/wjg.v23.i6.976