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Effect of toll-like receptor 3 agonist poly I:C on intestinal mucosa and epithelial barrier function in mouse models of acute colitis

AIM: To investigate potential effects of poly I:C on mucosal injury and epithelial barrier disruption in dextran sulfate sodium (DSS)-induced acute colitis. METHODS: Thirty C57BL/6 mice were given either regular drinking water (control group) or 2% (w/v) DSS drinking water (model and poly I:C groups...

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Detalles Bibliográficos
Autores principales: Zhao, Hong-Wei, Yue, Yue-Hong, Han, Hua, Chen, Xiu-Li, Lu, Yong-Gang, Zheng, Ji-Min, Hou, Hong-Tao, Lang, Xiao-Meng, He, Li-Li, Hu, Qi-Lu, Dun, Zi-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311109/
https://www.ncbi.nlm.nih.gov/pubmed/28246473
http://dx.doi.org/10.3748/wjg.v23.i6.999