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Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly

The type III secretion system (T3SS) is a bacterial virulence factor expressed by dozens of Gram-negative pathogens but largely absent from commensals. The T3SS is an attractive target for antimicrobial agents that may disarm pathogenic bacteria while leaving commensal populations intact. We previou...

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Detalles Bibliográficos
Autores principales: Morgan, Jessica M., Duncan, Miles C., Johnson, Kevin S., Diepold, Andreas, Lam, Hanh, Dupzyk, Allison J., Martin, Lexi R., Wong, Weng Ruh, Armitage, Judith P., Linington, Roger G., Auerbuch, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311113/
https://www.ncbi.nlm.nih.gov/pubmed/28217742
http://dx.doi.org/10.1128/mSphere.00030-17