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Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer
E2F transcription factors are important regulators of the cell cycle, and unrestrained activation of E2F-dependent transcription is considered to be an important driver of tumor formation and progression. Although highly expressed in normal skin and skin cancer, the role of the atypical E2Fs, E2F7 a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311251/ https://www.ncbi.nlm.nih.gov/pubmed/27452520 http://dx.doi.org/10.1038/onc.2016.251 |