CtIP-Specific Roles during Cell Reprogramming Have Long-Term Consequences in the Survival and Fitness of Induced Pluripotent Stem Cells

Acquired genomic instability is one of the major concerns for the clinical use of induced pluripotent stem cells (iPSCs). All reprogramming methods are accompanied by the induction of DNA damage, of which double-strand breaks are the most cytotoxic and mutagenic. Consequently, DNA repair genes seem...

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Detalles Bibliográficos
Autores principales: Gómez-Cabello, Daniel, Checa-Rodríguez, Cintia, Abad, María, Serrano, Manuel, Huertas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311465/
https://www.ncbi.nlm.nih.gov/pubmed/28065643
http://dx.doi.org/10.1016/j.stemcr.2016.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311465/
https://www.ncbi.nlm.nih.gov/pubmed/28065643
http://dx.doi.org/10.1016/j.stemcr.2016.12.009

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