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The conserved SNARE SEC-22 localizes to late endosomes and negatively regulates RNA interference in Caenorhabditis elegans

Small RNA pathways, including RNA interference (RNAi), play crucial roles in regulation of gene expression. Initially considered to be cytoplasmic, these processes have later been demonstrated to associate with membranes. For example, maturation of late endosomes/multivesicular bodies (MVBs) is requ...

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Detalles Bibliográficos
Autores principales: Zhao, Yani, Holmgren, Benjamin T., Hinas, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311485/
https://www.ncbi.nlm.nih.gov/pubmed/27974622
http://dx.doi.org/10.1261/rna.058438.116