Cargando…

Inhibition of nonsense-mediated RNA decay by ER stress

Nonsense-mediated RNA decay (NMD) selectively degrades mutated and aberrantly processed transcripts that contain premature termination codons (PTC). Cellular NMD activity is typically assessed using exogenous PTC-containing reporters. We overcame some inherently problematic aspects of assaying endog...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhelin, Vuong, John K., Zhang, Min, Stork, Cheryl, Zheng, Sika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311500/
https://www.ncbi.nlm.nih.gov/pubmed/27940503
http://dx.doi.org/10.1261/rna.058040.116