Inhibition of HIV-1 Gag–membrane interactions by specific RNAs

HIV-1 particle assembly, which occurs at the plasma membrane (PM) of cells, is driven by the viral polyprotein Gag. Gag recognizes phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)], a PM-specific phospholipid, via the highly basic region (HBR) in its N-terminal matrix (MA) domain. The HBR is als...

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Detalles Bibliográficos
Autores principales: Todd, Gabrielle C., Duchon, Alice, Inlora, Jingga, Olson, Erik D., Musier-Forsyth, Karin, Ono, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311501/
https://www.ncbi.nlm.nih.gov/pubmed/27932583
http://dx.doi.org/10.1261/rna.058453.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311501/
https://www.ncbi.nlm.nih.gov/pubmed/27932583
http://dx.doi.org/10.1261/rna.058453.116

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