Cargando…

Inhibition of HIV-1 Gag–membrane interactions by specific RNAs

HIV-1 particle assembly, which occurs at the plasma membrane (PM) of cells, is driven by the viral polyprotein Gag. Gag recognizes phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)], a PM-specific phospholipid, via the highly basic region (HBR) in its N-terminal matrix (MA) domain. The HBR is als...

Descripción completa

Detalles Bibliográficos
Autores principales:	Todd, Gabrielle C., Duchon, Alice, Inlora, Jingga, Olson, Erik D., Musier-Forsyth, Karin, Ono, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5311501/ https://www.ncbi.nlm.nih.gov/pubmed/27932583 http://dx.doi.org/10.1261/rna.058453.116

Ejemplares similares

Membrane Binding and Subcellular Localization of Retroviral Gag Proteins Are Differentially Regulated by MA Interactions with Phosphatidylinositol-(4,5)-Bisphosphate and RNA
por: Inlora, Jingga, et al.
Publicado: (2014)

Noncoding RNAs in Retrovirus Replication
por: Duchon, Alice A., et al.
Publicado: (2018)

Distinct binding interactions of HIV-1 Gag to Psi and non-Psi RNAs: Implications for viral genomic RNA packaging
por: Webb, Joseph A., et al.
Publicado: (2013)

Functional Equivalence of Retroviral MA Domains in Facilitating Psi RNA Binding Specificity by Gag
por: Rye-McCurdy, Tiffiny, et al.
Publicado: (2016)

HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit
por: Jin, Danni, et al.
Publicado: (2023)

Progress and outlook in structural biology of large viral RNAs
por: Cantara, William A., et al.
Publicado: (2014)

Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging
por: Duchon, Alice, et al.
Publicado: (2021)

Relationship between HIV-1 Gag Multimerization and Membrane Binding
por: Sumner, Christopher, et al.
Publicado: (2022)

Conservation of tRNA mimicry in the 5′-untranslated region of distinct HIV-1 subtypes
por: Comandur, Roopa, et al.
Publicado: (2017)

New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging
por: Olson, Erik D., et al.
Publicado: (2015)

Dynamic Association between HIV-1 Gag and Membrane Domains
por: Hogue, Ian B., et al.
Publicado: (2012)

New insights into retroviral Gag–Gag and Gag–membrane interactions
por: Maldonado, José O., et al.
Publicado: (2014)

Transfer RNAs: A treasure trove that keeps on giving
por: Gopalan, Venkat, et al.
Publicado: (2023)

Phosphomimetic S207D Lysyl–tRNA Synthetase Binds HIV-1 5′UTR in an Open Conformation and Increases RNA Dynamics
por: Cantara, William A., et al.
Publicado: (2022)

Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice
por: Saha, Ipsita, et al.
Publicado: (2021)

FRET analysis of HIV‐1 Gag and GagPol interactions
por: Takagi, Shimon, et al.
Publicado: (2017)

Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity
por: Monde, Kazuaki, et al.
Publicado: (2017)

Membrane interaction of retroviral Gag proteins
por: Dick, Robert A., et al.
Publicado: (2014)

Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein
por: Kankia, Besik I., et al.
Publicado: (2005)

Mechanistic differences between HIV-1 and SIV nucleocapsid proteins and cross-species HIV-1 genomic RNA recognition
por: Post, Klara, et al.
Publicado: (2016)

Induction of HIV-specific T-cell responses by gag
por: Van Gulck, Ellen, et al.
Publicado: (2006)

The tumour suppressor APC promotes HIV-1 assembly via interaction with Gag precursor protein
por: Miyakawa, Kei, et al.
Publicado: (2017)

Specific Interaction of DARPin with HIV-1 CA(NTD) Disturbs the Distribution of Gag, RNA Packaging, and Tetraspanin Remodelling in the Membrane
por: Moonmuang, Sutpirat, et al.
Publicado: (2022)

Specific inter-domain interactions stabilize a compact HIV-1 Gag conformation
por: Lin, Chen, et al.
Publicado: (2019)

Real-Time Visualization of HIV-1 GAG Trafficking in Infected Macrophages
por: Gousset, Karine, et al.
Publicado: (2008)

Nucleocapsid Promotes Localization of HIV-1 Gag to Uropods That Participate in Virological Synapses between T Cells
por: Llewellyn, G. Nicholas, et al.
Publicado: (2010)

HIV-1 Gag release from yeast reveals ESCRT interaction with the Gag N-terminal protein region
por: Meusser, Birgit, et al.
Publicado: (2021)

Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane
por: Vlach, Jiri, et al.
Publicado: (2015)

Binding mechanism of the matrix domain of HIV-1 gag on lipid membranes
por: Monje-Galvan, Viviana, et al.
Publicado: (2020)

Early HIV-1 Gag Assembly on Lipid Membrane with vRNA
por: Zhou, Anne X.-Z., et al.
Publicado: (2023)

Regulation of HIV-Gag Expression and Targeting to the Endolysosomal/Secretory Pathway by the Luminal Domain of Lysosomal-Associated Membrane Protein (LAMP-1) Enhance Gag-Specific Immune Response
por: Godinho, Rodrigo Maciel da Costa, et al.
Publicado: (2014)

Evolution of acceptor stem tRNA recognition by class II prolyl-tRNA synthetase
por: An, Songon, et al.
Publicado: (2008)

Anticodon-like binding of the HIV-1 tRNA-like element to human lysyl-tRNA synthetase
por: Liu, Sheng, et al.
Publicado: (2016)

HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness
por: Nikolaitchik, Olga A., et al.
Publicado: (2023)

Distinct Contributions of Different Domains within the HIV-1 Gag Polyprotein to Specific and Nonspecific Interactions with RNA
por: Kroupa, Tomas, et al.
Publicado: (2020)

Modulation of HIV-1 Gag/Gag-Pol frameshifting by tRNA abundance
por: Korniy, Natalia, et al.
Publicado: (2019)

Effects of reduced gag cleavage efficiency on HIV-1 Gag-Pol package
por: Lin, Yi-Ru, et al.
Publicado: (2022)

Identification of a novel mutation in the APTX gene associated with ataxia-oculomotor apraxia
por: Inlora, Jingga, et al.
Publicado: (2017)

Isolated Congenital Anosmia and CNGA2 Mutation
por: Sailani, M. Reza, et al.
Publicado: (2017)

Investigation of HIV-1 Gag binding with RNAs and lipids using Atomic Force Microscopy
por: Chen, Shaolong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_km7mg9u4rrrs0nn41k20tbu41g